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Search Results for " histone H3 phosphorylation "

ターゲット

4

阻害剤

7

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
TQ0059 Ilorasertib ABT-348 VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: ...
T36979 Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt) Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)
Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.3 sequence and is biotinylated via a C-terminal GK linker. Unlike histone H3.1 and H3...
T36576 Histone H3 (21-44)-GK-biotin (trifluoroacetate salt) Histone H3 (21-44)-GK-biotin (trifluoroacetate salt)
Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences and is biotinylated via a C-terminal GK linker. Histone H3 (21-44...
T68458 Fostriecin (free base)
Fostriecin (free base) is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4) (IC50s = 3.2 and 3 nM, respectively). It less effectively inhibits topoisomerase II and PP1 (IC50s = 40 and 131 μM...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-02899 VRK1 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream targe...
TMPY-04420 TLK1 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper c...
TMPY-03341 ASF1B Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
The histone chaperone anti-silencing factor 1a (ASF1a) interacts with MDC1 and is recruited to sites of DSBs to facilitate the interaction of phospho-ATM with MDC1 and phosphorylation of MDC1, which are required for the ...
TMPY-02510 HIST2H2BE Protein, Human, Recombinant Human E. coli
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. Histone proteins exhibit two levels of diversity: 1. evolutionary diversity between species and...
TMPH-02274 JAK2 Protein, Human, Recombinant (His) Human E. coli
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cyto...
TMPH-02815 Nucleophosmin Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome ...
TMPY-04385 ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP ...